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Basophils are immune cells derived from bone marrow stem cells. While basophils are not very common, their presence in the blood can be associated with a wide range of activities in the body, including allergic reactions and infections. Basophil percentage is the portion of basophils among white blood cells in a sample. (source, source)
Generally, low basophil levels are considered to be a sign of good health. These levels can be influenced by physiological factors relating to bone marrow, where these immune cells are produced. Low levels may indicate thyroid overactivity. (source, source)
Low basophil count usually does not require any specific treatment unless it is associated with a specific illness. There is no suggested nutritional, lifestyle, or supplement-based intervention.
High blood basophil levels can stem from physiological factors related to immune system function, as basophils are a type of white blood cell involved in allergic reactions and inflammation. Nutritionally, dietary factors, such as allergies to specific foods, may influence basophil levels in the blood. (source, source)
Prioritize vegetables: Basophil count has been associated with low vegetable intake. (source) A regular diet of high vegetable intake correlates to a lower inflammatory profile for white blood cells. In particular, green leafy vegetables like spinach and kale are high in dietary nitrate concentrations, which have been linked to lower levels of oxidative stress and promote a healthy gut microbiome. Together, vegetables promote a multifactorial approach to reducing basophil count. (source) Recommendation: Consume four servings of vegetables daily.
Avoid allergens and Irritants: Basophils have been shown to play a major role in the body's response to allergens and other irritants. (source, source) Recommendation: Understand any allergens or irritants (such as pollens, foods, or other substances) personal to you and work to avoid them to decrease excess environmental stress load.
Supplement with quercetin: Quercetin has been shown to have anti-allergic effects by inhibiting the expression of CD63 and CD203c, markers of basophil cell activation and various allergies, and subsequent histamine response. (source, source) Recommendation: Supplement with at least 200 mg of quercetin.
