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Serum creatinine concentrations can be influenced by multiple factors including daily activity and dietary habits. Often, its presence in the blood is used as a marker of kidney function. (source, source)
Low serum creatinine levels can stem from physiological factors involving muscle mass and kidney function, as creatinine is a byproduct of muscle metabolism that is filtered by the kidneys. Further, insufficient protein intake or inadequate muscle development can contribute to lower creatinine levels. (source, source)
Limit foods high in fiber: Daily fiber intake has been shown to reduce creatinine levels. (source) Fiber increases the bulk of the stool and provides a fecal route of excretion for nitrogenous waste, including creatinine. (source, source) Further, fiber aids in supporting bacterial creatinase, which breaks down creatinine, in the intestine. (source) Limiting fiber intake regulates creatinine levels in the body. Recommendation: Monitor and limit excess intake of fiber-rich foods, like oats, beans, and whole grains.
Exercise at a high intensity: High-intensity resistance training increases creatinine levels. (source) Exercise induces muscle damage that results in elevated creatinine levels. (source) Recommendation: Recommendation: Follow a structured program ensuring at least 75 minutes of 75% Max Heart Rate or greater weekly.
Elevated serum creatinine levels may arise from physiological factors related to kidney function, as creatinine is a waste product filtered out by the kidneys. Nutritionally, factors like excessive intake of protein-rich foods can contribute to higher creatinine levels, as the breakdown of protein produces creatinine. (source, source)
Prioritize fiber-rich foods: Daily fiber intake has been shown to reduce creatinine levels. (source) Fiber increases the stool bulk and provides a fecal route of excretion for nitrogenous waste, including creatinine, resulting in decreased levels of creatinine in the body. (source, source) Further, fiber aids in supporting bacterial creatinase, which breaks down creatinine, in the intestine. (source) Recommendation: Incorporate fiber-rich foods with the target of at least 30 g of fiber per day.
One serving examples: Chia Seeds (2 tbs), Flaxseeds (2 tbs), Lentils (1 cup), Steel Cut Oats (1 cup), Avocado (1 medium Avocado)
Prioritize proper hydration: Dehydration associated with exercise has been shown to raise markers of kidney damage. (source) Dehydration decreases the kidneys' ability to metabolize waste, including creatinine. (source) Ensuring adequate water intake regulates creatinine concentrations in the body. Recommendation: Drink at least 0.5 fl oz of water per pound body weight per day.
Supplement with vitamin C: Low vitamin C is associated with high creatinine concentrations. (source) Vitamin C supplementation improves endothelial function of the kidneys, resulting in enhanced kidney function, including the ability to metabolize and clear waste, like creatinine, from the blood. (source) Recommendation: Supplement with at least 100 mg of vitamin C daily.
